Use of Human Fetal Tissue in Bionic and Biomaterial Devices‪.‬

Abstract: The principle of cell transplantation in bionic or implantable devices as a replacement of diseased or lost tissue function, have many potential fields of application. The hypoantigenic fetal tissue has the potentialities to make a perfect non-irritant, i.e. biofriendly interface in case of different synthetic / metallic implants in medicine and surgery. For example, any stent in the body, be it in the prostate, pancreas, common bile duct or coronary artery, can be made much more biofreindly using a fetal endothetial cell lining and this can also lead to a minimization of progressive platelet and other cellular interaction/ vis a vis on degradation and it can help extend the life expectancy of these stents. In case of orthopedic surgery, e.g. hip knee or shoulder replacement prostheses, if allowed to be covered with fetal cells, they too can help extend the life of the implant by the biofriendly interface formation which can minimize the lining of tissue and inert tissue interface interactions and thus prevent T[H.sub.2] cellular responses by fibroblast proliferation and other tissue specific degranulation / degradation attempts by the host tissue. Fortunately, technology today has enabled the storage and preservation of fetal tissue for a significant period of time and supply and demand can thus, coincide.