Antibiotic Sensitivity Pattern of Common Bacterial Pathogens in NICU and Neonatal Ward in Hamedan Province of Iran (Neonatal Intensive Care Unit ) (Report‪)‬

1. INTRODUCTION There has been high incidence of antimicrobial resistance in bacterial infections in different parts of a country and also in any hospital [1-3]. Different mechanisms are involved in drug resistance of microorganisms. It may be genetic or non genetic in origin [4]. Widespread use of broadspectrum antibiotics is the most important factor, so antibiotic control policy has great importance in drug resistance control [5]. The incidence of infections in hospitalized neonates is very high. After widespread use of antibiotics in agriculture industry and medicine from 1950, antibiotics resistance in common pathogenic agents had increasingly emerged [6]. In developed countries constant investigation in this field had done for identifying antibiotic resistance pattern. Recently, the spectrum and resistance of the pathogenic bacteria have constantly changed year after year because of wide application of antimicrobial drugs [5-9]. It is necessary to treat neonatal infections by empirical use of antimicrobial drugs as soon as possible to reduce the mortality of them. It is based on the knowledge of epidemiology of bacterial susceptibility pattern in each area [6-15]. This study had done for identifying antimicrobial susceptibility pattern in a western province of Iran in neonatal ward to help the treatment of infected neonates.