It has been almost two years since the Michaluk virus outbreak began, and Kimberly Gellar has helped her newfound friends establish Woodside, a walled-in community of survivors in South Carolina, led by a committee of the best, brightest, and most heroic among them. But underneath the veneer of simplicity that their day-to-day lives become, not all is as it seems. Dr. Derek Rivers, a former CDC scientist, has created the most hopeful version of a cure for the virus and has tested it on a single subject, who promptly begins showing strange and concerning side effects.
After the members of a supply run bring back a set of twin survivors they've rescued, a horde of infected follow them back to Woodside. Within hours, the community is besieged by the infected. Desperate to get the potential cure out of their safe haven before the infected get in, Kimberly smuggles it out of Woodside to search for a still-operational CDC facility with only one person to guide and protect her.
As the community collapses and the lives of the survivors are threatened, can Kimberly get the cure to where it can do some good, and can she get help to Woodside before the friends she left behind end up dead at the hands of the infected after nearly two years of survival?