Multiple Pd-Catalyzed Reactions in the Synthesis of Natural Products, Drugs, And Materials (Report‪)‬

INTRODUCTION In modern synthesis, a paradigm shift has occurred in recent years; whereas, over the last decades the main focus was on stereoselectivity, nowadays the efficiency of chemical procedures, which can be defined as increase in complexity per transformation, the preservation of the natural resources, and the ecological benefits combined with economical advantages are the objectives in modern synthesis. Such an approach is not only valuable for our environment but also for industrial processes and will have a great impact on production. As a recent example I would like to mention the efficient synthesis of Tamiflu, an important antiviral drug, by a domino process [1].