The Last Trail (Barnes & Noble Digital Library‪)‬

This 1909 novel, set in Ohio, is the sequel to Spirit of the Border (1906) and rounds out the trilogy begun with Betty Zane (1903).  It features young Jonathan Zane and his partner, the mysterious woodsman known as La Vent de la Mort—the Wind of Death—and is based on the history of Grey's ancestors. The men deal with hostile Native Americans, plains famers, and Jonathan’s obsessive new lover.