Clinical Study to Evaluate the Efficacy of a Compound Unani Herbal Formulation Sharbat-E-Unsul Murakkab in Sual-E-Muzmin (Chronic Bronchitis) (Global Dispensary) (Clinical Report‪)‬

Introduction Chronic bronchitis is a common ailment of respiratory systems manifesting as productive cough and dyspnea due to mucosal irritation caused by smoking, occupational irritants, bacterial and viral infections (Davidson 1971). In winter there is worsening of the patient's condition which is known as acute exacerbation of chronic bronchitis or winter cough (Davidson 1971). It is usually a progressive disease punctuated by exacerbation and remissions. Chronic bronchitis is widely prevalent worldwide and according to WHO/WB the prevalence of chronic obstructive pulmonary disease (COPD) in 1990 was estimated at 9.34/1000 men, 7.33/1000 women (National Vital Statistics 2003). Mainly bronchodilators and antibiotics are required to treat chronic bronchitis but on each acute exacerbation there is progressive decline in ventillatory function, exercise capacity and health status, with increased financial burden on hospitalisation. There is risk of side effects and development of bacterial resistance to antibiotics (Isselbacher 1994). Ventillatory and cardiac failure are the most common complications leading to death (Haslet 1999).